Promethazine with codeine syrup is indicated for that temporary relief of coughs and higher respiratory symptoms connected with allergy or the widespread chilly.
Children Postmarketing cases of respiratory despair, including fatalities, are already reported with use of promethazine in pediatric people. Concomitant administration with other respiratory depressants may perhaps improve the hazard of respiratory depression.
Administration of codeine could possibly be accompanied by histamine launch and should be applied with caution in atopic kids.
To help you stop withdrawal, your health practitioner may well decrease your dose little by little. Withdrawal is more possible When you've got made use of this medication for a long period (quite a lot of months) or in large doses. Explain to your doctor or pharmacist immediately When you've got withdrawal.
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The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers under six many years of age.
Due to the threats of addiction, abuse, and misuse with opioids, even at advised doses [see Warnings and Safeguards (five.one)], reserve Promethazine HCl and Codeine Phosphate Oral Resolution to be used in Grownup people for whom the advantages of cough suppression are envisioned to outweigh the pitfalls, and in whom an ample evaluation from the etiology of your cough has actually been produced.
The phosphate salt of codeine happens as white, needle-shaped crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and a bit soluble in Liquor.
Read the Medication Guide provided by your pharmacist before you start having codeine/promethazine and each time you can get a refill. For those who have any queries, talk to your health care provider or pharmacist.
Results around the Gastrointestinal Tract as well as other Easy Muscle Codeine triggers a reduction in motility affiliated with an increase in sleek muscle mass tone inside the antrum of the abdomen and duodenum. Digestion of food in the small intestine is delayed and propulsive contractions are lessened.
Instruct nursing moms to talk to the baby's medical professional right away when they notice these signals and, if they cannot reach the medical doctor without delay, Promethazine codeine syrup to take the little one to an crisis area or connect with 911 (or regional unexpected emergency products and services).
This medication may perhaps cause you to much more sensitive on the Sunshine. Limit your time and effort in the Solar. Stay clear of tanning booths and sunlamps. Use sunscreen and don protecting clothing when outdoors. Explain to your health practitioner immediately if you will get sunburned or have pores and skin blisters/redness.
Narcotic analgesics or cough suppressants, which includes codeine, really should not be Employed in asthmatic people (see CONTRAINDICATIONS). Nor must they be Employed in acute febrile health issues related to productive cough or in Serious respiratory illness where interference with ability to clear the tracheobronchial tree of secretions would've a deleterious effect on the individual's respiratory operate.
The opioid antagonists, naloxone and nalmefene, are precise antidotes for respiratory depression ensuing from opioid overdose. For clinically considerable respiratory or circulatory melancholy secondary to codeine overdose, administer an opioid antagonist. An antagonist should not be administered during the absence of clinically major respiratory melancholy. Because the duration of opioid reversal is predicted for being a lot less than the duration of action of codeine in Promethazine HCl and Codeine Phosphate Oral Alternative, carefully watch the individual right until spontaneous respiration is reliably reestablished.